Scientist Ii

Job Title:Scientist II
Location: Framingham, MA 01701
Duration: 12 months-Contract
Client-Pharma
Job Description:
Client"s Large Molecule Research department has an exciting opportunity for a structural biologist to contribute to pharmaceutical research. The scientist will help expand the successful cryo-EM unit in our structural biology group that is generating high-resolution structures of protein complexes and Client structure-function research. The candidate will be responsible for all aspects of the single particle cryo-EM process, from sample preparation and data collection through 3-D reconstruction. We are seeking an outstanding structural biologist and collaborator who will impact and accelerate our portfolio.
Key Responsibilities:
Effective communication with project teams for coordinated use of structural biology to accelerate drug discovery.
Deliver structural biology project support for clients project teams in a fast-paced dynamic environment.
Deep understanding and analysis of data and results with ability to communicate findings and project impact to global multidisciplinary project teams.
Basic qualifications:
PhD in protein biochemistry, biophysics, structural biology, or related discipline. Candidates with only MSc degree and with an appropriate experience will be considered.
Expertise in cryo-EM grid preparation and screening and data collection.
Single particle EM data processing, three-dimensional structure determination and model building.
Cryo-EM research contributions demonstrated through authorship in peer-reviewed publication(s).
Preferred Qualifications:
Self-motivated and able to handle multiple challenging projects in parallel
Excellent communication and presentation skills to enhance team-based progress
Ability to work independently and effectively within timelines and collaborate in a highly multidisciplinary environment
Experience with recombinant protein techniques including construct design, protein expression, purification, and biophysical characterization. Experience in HPLC, FPLC, PAGE is a plus.
Computational skills are preferred, but not required. Basic understanding of Linux terminal usage/shell-scripting is required.
Employment Type: Contractor