Job DescriptionThe mission of our team is to translate novel drug-delivery technologies to treat children with brain tumors. The brain has a natural barrier that prevents toxins and other agents from reaching the brain. This same barrier also limits the access of systemic treatments, including chemotherapy, targeted therapy, and immunotherapy, from reaching the tumor. We are interested in exploring the usage of focused ultrasound (FUS) and convection-enhanced delivery (CED). Using targeted ultrasound, or FUS, with microbubbles, the blood-brain barrier (BBB) can temporarily and reversibly open to allow for enhanced drug delivery to fight brain tumors. In addition, we are also exploring the use of direct catheter delivery of drugs to brain tumors using CED. We are focusing on identifying novel methods to treat Pediatric Brain tumors using new Drug Delivery Approaches and novel agents. Our goal is to translate into Novel Clinical Trials for children suffering from brain tumors.We are seeking candidates with experience in cell culture work, molecular biology, and preclinical tumor models. Successful candidates will be highly motivated individuals with a doctoral degree in Neurology, Oncology, or Immunology, have excellent communication skills, be able to function independently, and participate as part of a dynamic team. The successful candidate will be involved in generating preclinical data that will lead to the design a number of novel clinical studies in children with high-grade gliomas and other brain tumors.Work Location:Fralin Biomedical Research Institute at VTC, Roanoke, VAhttps://fbri.vtc.vt.edu/Documents Needed to Apply:Curriculum VitaeCover LetterList of ReferencesIf interested or have any questions regarding this position, please email ****** Qualifications? PhD in Oncology, Neuroscience, Immunology, or appropriate related disciplines. PhD must be awarded no more than four years prior to the effective date of appointment with a minimum of one year eligibility remaining.? Creative, independent, and highly motivated, with good communication skills.? Demonstrated publication of research findings in peer-reviewed journals.? Experience in cell biology, molecular biology, and preclinical animal models.Preferred Qualifications? Experience with flow cytometry.? Experience with RNA sequencing and analysis.? Experience with gene-editing techniques in cells or animals.Appointment TypeRestrictedSalary InformationCommensurate with experienceReview Date4/26/2024Additional InformationThe successful candidate will be required to have a criminal conviction check.About Virginia TechDedicated to its motto,Ut Prosim(That I May Serve), Virginia Tech pushes the boundaries of knowledge by taking a hands-on, transdisciplinary approach to preparing scholars to be leaders and problem-solvers. A comprehensive land-grant institution that enhances the quality of life in Virginia and throughout the world, Virginia Tech is an inclusive communitydedicated to knowledge, discovery, and creativity. The university offers more than 280 majors to a diverse enrollment of more than 36,000 undergraduate, graduate, and professional students in eight undergraduate colleges, a school of medicine, a veterinary medicinecollege, Graduate School , andHonors College . The university has a significant presence across Virginia, including theInnovation Campus in Northern Virginia; the Health Sciences and Technology Campus in Roanoke; sites in Newport News and Richmond; and numerousExtension offices andresearch centers . A leading global research institution, Virginia Tech conducts more than $500 million in research annually.Virginia Tech does not discriminate against employees, students, or applicants on the basis of age, color, disability, sex (including pregnancy), gender, gender identity, gender expression, genetic information, national origin, political affiliation, race, religion, sexual orientation, or military status, or otherwise discriminate against employees or applicants who inquire about, discuss, or disclose their compensation or the compensation of other employees or applicants, or on any other basis protected by law.If you are an individual with a disability and desire an accommodation, please contactBrittany ****** regular business hours at least 10 business days prior to the event.
