Job Description
Job Description
This position offers the opportunity to impact a growing portfolio of targeted therapies in a fast-paced and innovative research environment.
Our client is searching for a dynamic Associate Biology Scientist with experience interrogating cellular and molecular mechanisms as they relate to kinase target pathway modulation, off-target liabilities, and resistance.
Responsibilities:
Independently, develop, optimize, and proactively troubleshoot cellular screening assays.
Responsible for generating, processing, interpreting, and presenting data in cross functional team meetings
Proactively employ cell and molecular biology techniques, including gene targeting approaches and small molecule inhibition, to dissect mechanism of action.
Independently design, execute and document experiments to evaluate target dependency, off target liabilities, phenotypic responses and identifying resistance mechanisms.
Regularly share and present data with team members.
Requirements / Qualifications:
MS/BS in oncology, cellular biology, molecular biology, or related discipline with 1+ years of industry or relevant research experience is required.
Experience in developing and optimizing cell-based assays in multiple platforms (for example CTG, HTRF, AlphaLISA , FC, Jess-WB, NanoBret, Nanostring).
Experience with different molecular and cellular biology techniques (such as Western Blot).
Experience with genome editing (CRISPR or si/shRNA) for engineering cell line models is a plus.
Familiar with tumor models and establishing PK/PD/efficacy relationships and delivering PD readouts by western blots for in vivo tumor models.
Experience with standard software analytical tools, xlsx, Prism, or other synergy software.
Strong oral and written communication skills, as well as excellent documentation and organizational skills.
A team player, who listens effectively, invites response and discussion.
Company Description The Steely Group is a national preclinical, clinical, and commercial staffing firm and certified women's business enterprise. We partner with small, growing biotech, pharma, and gene therapy companies to help bring treatments to patients by providing flexible talent acquisition solutions including Contingent Search (Direct Hire & Contract Consultants) and Retained Executive Search.
Company Description
The Steely Group is a national preclinical, clinical, and commercial staffing firm and certified women's business enterprise. We partner with small, growing biotech, pharma, and gene therapy companies to help bring treatments to patients by providing flexible talent acquisition solutions including Contingent Search (Direct Hire & Contract Consultants) and Retained Executive Search.
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