A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.
Note: This is a four-year term-limited appointment.
The Ginsburg laboratory is looking for a Research Investigator to independently perform and manage research that examines the transport of secretory proteins from the ER to the Golgi. This work will involve sophisticated use of cell biologic and microscopic techniques, and the latest genomic technologies, including next-generation sequencing, CRISPR/CAS9 and proteomics. You will report directly to Dr. Ginsburg and will work full-time on-site.
Experimental responsibilities will include:
- Apply high throughput genomic CRISPR screens to identify novel components of the ER/Golgi secretory pathway concerning specific cargo proteins
- Characterize the full range of secreted proteins dependent on specific cellular cargo receptors
- Identify structural motifs within specific cargo receptors mediating their interaction with their corresponding cargo proteins
- Maintain bacterial and mammalian cell cultures and stocks
Non-experimental responsibilities will include:
- Provide consultation and advice to lab members in areas of expertise
- Assist PI in preparing manuscripts and grants
- Mentor the research work of junior trainees in the lab including postdoctoral fellows and undergraduate students
- Present research work at scientific platforms within and outside the Institute
- Ph.D. in relevant biology-related field
- Minimum four years of postdoctoral experience in cell biology, biochemistry and molecular biology
- Minimum three years of experience with cell biologic methods, characterizing Golgi structure and function, and corresponding defects in human disease
- Minimum three years of experience studying the regulation of redox homeostasis in the endoplasmic reticulum
- Minimum four years of experience supervising the research activities of graduate students, technicians, and undergraduate students
Benefits at the University of Michigan:
In addition to a career filled with purpose and opportunity, The University of Michigan offers a comprehensive benefits package to help you stay well, protect yourself and your family, and plan for a secure future. Benefits include:
- Generous time off
- A retirement plan that provides two-for-one matching contributions
- Many choices for comprehensive health insurance
- Dental, Vision, and Legal Insurance
- Life insurance
- Long-term disability coverage
- Flexible spending accounts for healthcare and dependent care expenses
- Maternity and Parental Leave
The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks are performed in compliance with the Fair Credit Reporting Act.
The Life Sciences Institute explores biological processes, structures, and functions at the finest scale to create impact on a global scale. With a diverse community of inquisitive minds and exceptional tools, we are a catalyst for breakthrough discoveries.
For more information on the Ginsburg laboratory:
The University of Michigan is an equal opportunity/affirmative action employer.
About University of Michigan - Ann Arbor
A great university is made so by its faculty and staff, and Michigan is recognized as one of the best universities to work for in the country. The Michigan culture is known for engaging faculty and staff in all facets of the university to create a workplace that is vibrant and stimulating.For two consecutive years, the Chronicle of Higher Education has placed U-M in its "Great Colleges to Work For" survey. In particular, the university earns high marks for strong relations between faculty and administrators, a collaborative system of governance, strong pay and benefits, and a healthy work/life balance.
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