Scientist I

Scientist I


Scientist I

Details of the offer

At AstraZeneca we work together across global boundaries to make an impact and find answers to
challenges. We do this with the upmost integrity even in the most difficult situations because we
are committed to doing the right thing. We continuously forge partnerships that help pursue
world-class medicines in new ways, combining our people's exceptional skills with those of people
from all over the globe.
The Clinical Pharmacology and Quantitative Pharmacology Department at AstraZeneca seeks an
experienced Scientist I to support development and implementation of bioanalytical and biomarker
assays of cell-based therapeutics to be located in South San Francisco, CA or Gaithersburg, MD.
Major Duties and Responsibilities:
The job-holder will serve as a bioanalytical and biomarker scientist on pre-clinical and clinical
programs of novel cell-based therapeutics. Responsibilities include development (hands-on
laboratory work), qualification and implementation of bioanalytical/biomarker assays to quantify
product quantities and pharmacodynamic activities thereof for
AstraZeneca cell-based therapeutics. In addition, the candidate will manage interactions with
contract research organizations (CROs), including assay transfer, validation, trouble-shooting and
analysis of resulting data.
PhD in immunology/cell biology/microbiology or related field; 1-3 years of academic, pharmaceutical
or biotechnology industry experience in cell-based therapeutics or immunology.
* Demonstrated ability to contribute to drug development process with a strong track record of
identifying creative solutions to complex problems.
* Previous management of CRO interactions &/or academic collaborations.
* Must be motivated and capable of working independently as well as in a team setting.
* Has track record of generating high-quality work with publication record in the relevant
* Must have strong written and verbal communication skills.
Special Skills/Abilities:
* Strong knowledge of cell biology and immunology
* Expertise with cell characterization technologies include high-parameter flow cytometry (design
and implementation of 12+ parameter assays using BD Symphony and/or Cytek Aurora instruments) and
ELISPOT-based assays
* Understanding and facility with modern multi-parametric analysis techniques (e.g. tSNE, SPADE,
* Familiarity with molecular techniques associated with CAR T production (viral transfection,
* Familiarity with clinical/translational assay qualification.
Next Steps - Apply today!
To be considered for this exciting opportunity, please complete the full application on our website
at your earliest convenience - it is the only way that our Recruiter and Hiring Manager can know
that you feel well qualified for this opportunity. If you know someone who would be a great fit,
please share this posting with them.
Salary: Negotiable

Source: Jooble_Org


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